ID   DEF69_ARATH             Reviewed;          96 AA.
AC   Q9FL73; A0MFP1;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Defensin-like protein 69;
DE   Flags: Precursor;
GN   OrderedLocusNames=At5g54220; ORFNames=MDK4.4;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9679202; DOI=10.1093/dnares/5.2.131;
RA   Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence
RT   features of the regions of 1,381,565 bp covered by twenty one physically
RT   assigned P1 and TAC clones.";
RL   DNA Res. 5:131-145(1998).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
RN   [4]
RP   GENE FAMILY.
RX   PubMed=15955924; DOI=10.1104/pp.105.060079;
RA   Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT   "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL   Plant Physiol. 138:600-610(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABK28756.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AB010695; BAB10745.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED96469.1; -; Genomic_DNA.
DR   EMBL; DQ447074; ABE66248.1; -; mRNA.
DR   EMBL; DQ653367; ABK28756.1; ALT_SEQ; mRNA.
DR   RefSeq; NP_200233.1; NM_124802.3.
DR   AlphaFoldDB; Q9FL73; -.
DR   STRING; 3702.AT5G54220.1; -.
DR   PaxDb; Q9FL73; -.
DR   PRIDE; Q9FL73; -.
DR   EnsemblPlants; AT5G54220.1; AT5G54220.1; AT5G54220.
DR   GeneID; 835510; -.
DR   Gramene; AT5G54220.1; AT5G54220.1; AT5G54220.
DR   KEGG; ath:AT5G54220; -.
DR   Araport; AT5G54220; -.
DR   TAIR; locus:2162575; AT5G54220.
DR   HOGENOM; CLU_175051_0_0_1; -.
DR   InParanoid; Q9FL73; -.
DR   OMA; YEGCNAT; -.
DR   OrthoDB; 1533053at2759; -.
DR   PhylomeDB; Q9FL73; -.
DR   PRO; PR:Q9FL73; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FL73; baseline and differential.
DR   Genevisible; Q9FL73; AT.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..96
FT                   /note="Defensin-like protein 69"
FT                   /id="PRO_0000379647"
FT   DISULFID        37..86
FT                   /evidence="ECO:0000250"
FT   DISULFID        41..64
FT                   /evidence="ECO:0000250"
FT   DISULFID        50..84
FT                   /evidence="ECO:0000250"
FT   DISULFID        54..85
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   96 AA;  10468 MW;  7D3E9EC633D413AF CRC64;
     MGSSKLLVAF TLIVMMTISY DLFTGIGIDA RTVPPTCYES CNATFQNPEC NKMCVGLAYK
     DGSCIYPPPE VDGLPPKRPY FPRCCCNPII LSPPSP