DEF78_ARATH
ID DEF78_ARATH Reviewed; 89 AA.
AC Q9SL74; A0MJT1;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Defensin-like protein 78;
DE Flags: Precursor;
GN OrderedLocusNames=At2g20070; ORFNames=T2G17.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17565583; DOI=10.1111/j.1365-313x.2007.03136.x;
RA Silverstein K.A.T., Moskal W.A. Jr., Wu H.C., Underwood B.A., Graham M.A.,
RA Town C.D., VandenBosch K.A.;
RT "Small cysteine-rich peptides resembling antimicrobial peptides have been
RT under-predicted in plants.";
RL Plant J. 51:262-280(2007).
RN [5]
RP GENE FAMILY.
RX PubMed=15955924; DOI=10.1104/pp.105.060079;
RA Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL Plant Physiol. 138:600-610(2005).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABK27944.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC006081; AAD24389.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06961.1; -; Genomic_DNA.
DR EMBL; DQ446528; ABE65832.1; -; mRNA.
DR EMBL; DQ912230; ABK27944.1; ALT_SEQ; mRNA.
DR EMBL; EF182808; -; NOT_ANNOTATED_CDS; mRNA.
DR PIR; F84584; F84584.
DR RefSeq; NP_179597.1; NM_127565.4.
DR AlphaFoldDB; Q9SL74; -.
DR SMR; Q9SL74; -.
DR PaxDb; Q9SL74; -.
DR PRIDE; Q9SL74; -.
DR EnsemblPlants; AT2G20070.1; AT2G20070.1; AT2G20070.
DR GeneID; 816526; -.
DR Gramene; AT2G20070.1; AT2G20070.1; AT2G20070.
DR KEGG; ath:AT2G20070; -.
DR Araport; AT2G20070; -.
DR TAIR; locus:2061644; AT2G20070.
DR HOGENOM; CLU_2609304_0_0_1; -.
DR InParanoid; Q9SL74; -.
DR OMA; NTCCCKK; -.
DR OrthoDB; 1787499at2759; -.
DR PhylomeDB; Q9SL74; -.
DR PRO; PR:Q9SL74; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SL74; baseline and differential.
DR Genevisible; Q9SL74; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..30
FT /evidence="ECO:0000255"
FT CHAIN 31..89
FT /note="Defensin-like protein 78"
FT /id="PRO_0000379649"
FT DISULFID 40..75
FT /evidence="ECO:0000250"
FT DISULFID 44..67
FT /evidence="ECO:0000250"
FT DISULFID 52..73
FT /evidence="ECO:0000250"
FT DISULFID 56..74
FT /evidence="ECO:0000250"
SQ SEQUENCE 89 AA; 9312 MW; 8B5D3D4EF7D1A581 CRC64;
MANNMVASPY KNTFMMIALV LILLISGSEA RSNGIYDPMC PGVCGNLVKP DCNGLCHELG
FPAGGYCKPG NTCCCKKKDS GPVDVPPTA
