DEF95_ARATH
ID DEF95_ARATH Reviewed; 91 AA.
AC Q6NMS3; O49628;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Defensin-like protein 95;
DE Flags: Precursor;
GN OrderedLocusNames=At4g22235; ORFNames=T10I14.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY.
RX PubMed=15955924; DOI=10.1104/pp.105.060079;
RA Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL Plant Physiol. 138:600-610(2005).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q6NMS3-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA16773.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At4g22230 and At4g22235.; Evidence={ECO:0000305};
CC Sequence=CAB79178.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At4g22230 and At4g22235.; Evidence={ECO:0000305};
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DR EMBL; AL021712; CAA16773.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161556; CAB79178.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE84579.1; -; Genomic_DNA.
DR EMBL; BT010916; AAR24694.1; -; mRNA.
DR EMBL; BT011583; AAS46636.1; -; mRNA.
DR PIR; T04904; T04904.
DR RefSeq; NP_567657.1; NM_118349.3. [Q6NMS3-1]
DR AlphaFoldDB; Q6NMS3; -.
DR BioGRID; 13607; 1.
DR IntAct; Q6NMS3; 1.
DR STRING; 3702.AT4G22235.1; -.
DR PaxDb; Q6NMS3; -.
DR PRIDE; Q6NMS3; -.
DR ProteomicsDB; 222201; -. [Q6NMS3-1]
DR EnsemblPlants; AT4G22235.1; AT4G22235.1; AT4G22235. [Q6NMS3-1]
DR GeneID; 828318; -.
DR Gramene; AT4G22235.1; AT4G22235.1; AT4G22235. [Q6NMS3-1]
DR KEGG; ath:AT4G22235; -.
DR Araport; AT4G22235; -.
DR TAIR; locus:505006512; AT4G22235.
DR HOGENOM; CLU_2416305_0_0_1; -.
DR OMA; DEPCKVL; -.
DR PhylomeDB; Q6NMS3; -.
DR PRO; PR:Q6NMS3; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q6NMS3; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Alternative splicing; Antimicrobial; Disulfide bond; Fungicide;
KW Plant defense; Reference proteome; Secreted; Signal.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..91
FT /note="Defensin-like protein 95"
FT /id="PRO_0000379659"
FT DISULFID 31..76
FT /evidence="ECO:0000250"
FT DISULFID 38..63
FT /evidence="ECO:0000250"
FT DISULFID 47..73
FT /evidence="ECO:0000250"
FT DISULFID 51..75
FT /evidence="ECO:0000250"
SQ SEQUENCE 91 AA; 9689 MW; 76B240045BC0EB47 CRC64;
MGSLKLSTFA IVVCLSILLI SPIEVNGWGK CDLRKGLCRL ADTISTCDVP CRAVDSKYHG
GECLNVGGGQ GICWCCRDYD AAKSGAEKES M
