ID   DEFB_DRONO              Reviewed;          20 AA.
AC   P86385;
DT   05-SEP-2012, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2012, sequence version 1.
DT   25-MAY-2022, entry version 9.
DE   RecName: Full=Beta-defensin {ECO:0000303|PubMed:22044478};
DE   Flags: Fragment;
OS   Dromaius novaehollandiae (Emu).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Palaeognathae; Casuariiformes; Dromaiidae; Dromaius.
OX   NCBI_TaxID=8790;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE.
RC   TISSUE=Egg white {ECO:0000269|PubMed:22044478};
RX   PubMed=22044478; DOI=10.1016/j.gene.2011.10.021;
RA   Maehashi K., Matano M., Irisawa T., Uchino M., Kashiwagi Y., Watanabe T.;
RT   "Molecular characterization of goose- and chicken-type lysozymes in emu
RT   (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in
RT   emu egg white.";
RL   Gene 492:244-249(2012).
CC   -!- FUNCTION: Has bactericidal activity. {ECO:0000250|UniProtKB:Q6IV20}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q6IV20}.
CC   -!- SIMILARITY: Belongs to the beta-defensin family. {ECO:0000255}.
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DR   AlphaFoldDB; P86385; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Defensin; Direct protein sequencing;
KW   Disulfide bond; Secreted.
FT   CHAIN           1..>20
FT                   /note="Beta-defensin"
FT                   /id="PRO_0000419142"
FT   DISULFID        8..?
FT                   /evidence="ECO:0000250|UniProtKB:Q6IV20"
FT   DISULFID        15..?
FT                   /evidence="ECO:0000250|UniProtKB:Q6IV20"
FT   NON_TER         20
FT                   /evidence="ECO:0000303|PubMed:22044478"
SQ   SEQUENCE   20 AA;  2369 MW;  4C4A3E025F5A9D64 CRC64;
     LPRHTLHCVA YHGYCFHSKV