ID   DEFD4_SPIOL             Reviewed;          23 AA.
AC   P81569;
DT   06-DEC-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Defensin D4;
DE   AltName: Full=Antimicrobial peptide D4;
DE   AltName: Full=So-D4;
DE   Flags: Fragment;
OS   Spinacia oleracea (Spinach).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   Caryophyllales; Chenopodiaceae; Chenopodioideae; Anserineae; Spinacia.
OX   NCBI_TaxID=3562 {ECO:0000305};
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE.
RC   STRAIN=cv. Matador; TISSUE=Leaf;
RX   PubMed=9762899; DOI=10.1016/s0014-5793(98)01060-6;
RA   Segura A., Moreno M., Molina A., Garcia-Olmedo F.;
RT   "Novel defensin subfamily from spinach (Spinacia oleracea).";
RL   FEBS Lett. 435:159-162(1998).
CC   -!- FUNCTION: Antimicrobial peptide. Active against Fusarium spp., Gram-
CC       positive and Gram-negative bacterial pathogens.
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Distributed in the epidermal cell layer of leaves
CC       and in the subepidermal layer region of stems. Not in roots.
CC   -!- DEVELOPMENTAL STAGE: Present throughout the life of the leaf.
CC   -!- SIMILARITY: Belongs to the DEFL family. Group IV subfamily.
CC       {ECO:0000305}.
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DR   AlphaFoldDB; P81569; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Cell wall; Direct protein sequencing; Fungicide;
KW   Plant defense; Secreted.
FT   CHAIN           1..>23
FT                   /note="Defensin D4"
FT                   /id="PRO_0000074254"
FT   NON_TER         23
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   23 AA;  2623 MW;  E7CA1B8CB78C6D00 CRC64;
     MFFSSKKCKT VSKTFRGPCV RNA