ID   DEFI8_CAEEL             Reviewed;         486 AA.
AC   O01738;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 2.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=Differentially expressed in FDCP 8 homolog;
GN   ORFNames=F20H11.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SIMILARITY: Belongs to the DEF8 family. {ECO:0000305}.
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DR   EMBL; FO081189; CCD69775.1; -; Genomic_DNA.
DR   PIR; E88486; E88486.
DR   RefSeq; NP_498454.2; NM_066053.7.
DR   AlphaFoldDB; O01738; -.
DR   SMR; O01738; -.
DR   BioGRID; 41150; 1.
DR   IntAct; O01738; 1.
DR   STRING; 6239.F20H11.1; -.
DR   EPD; O01738; -.
DR   PaxDb; O01738; -.
DR   PeptideAtlas; O01738; -.
DR   EnsemblMetazoa; F20H11.1.1; F20H11.1.1; WBGene00017646.
DR   GeneID; 175933; -.
DR   KEGG; cel:CELE_F20H11.1; -.
DR   UCSC; F20H11.1; c. elegans.
DR   CTD; 175933; -.
DR   WormBase; F20H11.1; CE29769; WBGene00017646; -.
DR   eggNOG; KOG1829; Eukaryota.
DR   HOGENOM; CLU_034500_0_0_1; -.
DR   InParanoid; O01738; -.
DR   OMA; GHNPCCE; -.
DR   OrthoDB; 177737at2759; -.
DR   PhylomeDB; O01738; -.
DR   PRO; PR:O01738; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00017646; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd00029; C1; 1.
DR   InterPro; IPR046349; C1-like_sf.
DR   InterPro; IPR002219; PE/DAG-bd.
DR   InterPro; IPR025258; Zf-RING_9.
DR   Pfam; PF13901; zf-RING_9; 1.
DR   SMART; SM00109; C1; 2.
DR   SMART; SM01175; DUF4206; 1.
DR   SUPFAM; SSF57889; SSF57889; 1.
DR   PROSITE; PS50081; ZF_DAG_PE_2; 2.
PE   3: Inferred from homology;
KW   Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger.
FT   CHAIN           1..486
FT                   /note="Differentially expressed in FDCP 8 homolog"
FT                   /id="PRO_0000321919"
FT   ZN_FING         160..212
FT                   /note="Phorbol-ester/DAG-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00226"
FT   ZN_FING         393..459
FT                   /note="Phorbol-ester/DAG-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00226"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   486 AA;  56507 MW;  61E4873974949674 CRC64;
     MSSWCSSEDA HNQSSTPSTR SRKSSWLISK IDENEIDKEV QEMMDDWRRS NEAENHVECI
     KAALEYCRDK LKELLIDEED TEMDGKETKT KPINIVSNTE FPEDRDVLGN LVNCLDRQQK
     AARQQMYFDK IVQLGLERQA LQDEAVVSTS SPLDECRAEG HEFVMQPVRG GHNPCCEVCM
     HTIWRLVQWW RRCRVCGMRA HDKCAEEVKR VCAGVLSTRA KFELNTNLCE ERSLAEQEYQ
     CAECTAPICF DGVAEQEARL CDYSGELFCP NCHWNDVWSI PARIVHNLDS TPRPVCRAVK
     QLLAIIDHRP LIDINESTLS LIKFHKELRR VNELRRNFLL MKCYFVSCRT ARRLRILQYL
     NAHSHFVDNS VMYSPKELRE LCDGTLLPDL EQIHTVFRKH IEEECETCAG NGFFCELCDD
     INVDQKNKIL YPFTENTRSC ATCLAVYHKK CFERKSLNCP RCERRRKRTE IPKTLSSSDE
     KEAVRN