ID   DEFI_PALPR              Reviewed;          43 AA.
AC   P80407;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Defensin;
OS   Palomena prasina (Green shield bug) (Cimex prasinus).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC   Pentatomomorpha; Pentatomoidea; Pentatomidae; Pentatominae; Palomena.
OX   NCBI_TaxID=55431;
RN   [1]
RP   PROTEIN SEQUENCE, AND MASS SPECTROMETRY.
RC   TISSUE=Hemolymph, and Larval hemolymph;
RX   DOI=10.1016/0022-1910(95)00085-2;
RA   Chernysh S., Cociancich S., Briand J.-P., Hetru C., Bulet P.;
RT   "The inducible antibacterial peptides of the hemipteran insect Palomena
RT   prasina: identification of a unique family of proline-rich peptides and of
RT   a novel insect defensin.";
RL   J. Insect Physiol. 42:81-89(1996).
CC   -!- FUNCTION: Antibacterial peptide active against Gram-positive and Gram-
CC       negative bacteria.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- INDUCTION: By bacterial infection.
CC   -!- MASS SPECTROMETRY: Mass=4614.2; Mass_error=0.3; Method=Electrospray;
CC       Evidence={ECO:0000269|Ref.1};
CC   -!- SIMILARITY: Belongs to the invertebrate defensin family. Type 1
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU00710}.
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DR   AlphaFoldDB; P80407; -.
DR   SMR; P80407; -.
DR   GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IEP:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.30.10; -; 1.
DR   InterPro; IPR001542; Defensin_invertebrate/fungal.
DR   InterPro; IPR003614; Scorpion_toxin-like.
DR   InterPro; IPR036574; Scorpion_toxin-like_sf.
DR   Pfam; PF01097; Defensin_2; 1.
DR   SMART; SM00505; Knot1; 1.
DR   SUPFAM; SSF57095; SSF57095; 1.
DR   PROSITE; PS51378; INVERT_DEFENSINS; 1.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Defensin; Direct protein sequencing;
KW   Disulfide bond; Immunity; Innate immunity; Secreted.
FT   CHAIN           1..43
FT                   /note="Defensin"
FT                   /id="PRO_0000074473"
FT   DISULFID        3..34
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00710"
FT   DISULFID        20..39
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00710"
FT   DISULFID        24..41
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00710"
SQ   SEQUENCE   43 AA;  4648 MW;  391EF2E8869A694D CRC64;
     ATCDALSFSS KWLTVNHSAC AIHCLTKGYK GGRCVNTICN CRN