ID   DEF_MESMA               Reviewed;          61 AA.
AC   Q95P88; Q967L8;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Defensin-like peptide TXKs2;
DE            Short=BmTXKs2;
DE   Flags: Precursor;
OS   Mesobuthus martensii (Manchurian scorpion) (Buthus martensii).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Scorpiones; Buthida; Buthoidea; Buthidae; Mesobuthus.
OX   NCBI_TaxID=34649;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom gland;
RX   PubMed=11087122; DOI=10.1080/15216540050176601;
RA   Zhu S., Li W., Jiang D., Zeng X.;
RT   "Evidence for the existence of insect defensin-like peptide in scorpion
RT   venom.";
RL   IUBMB Life 50:57-61(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Shunyi Z., Wenxin L.;
RT   "Genomic sequence of BmTXKS2.";
RL   Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Antibacterial protein. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- SIMILARITY: Belongs to the invertebrate defensin family. {ECO:0000305}.
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DR   EMBL; AF156596; AAK61820.1; -; mRNA.
DR   EMBL; AF380941; AAK57517.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q95P88; -.
DR   SMR; Q95P88; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Antibiotic; Antimicrobial; Defensin; Disulfide bond; Secreted; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   PROPEP          20..22
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000428822"
FT   CHAIN           23..61
FT                   /note="Defensin-like peptide TXKs2"
FT                   /id="PRO_0000428823"
FT   DISULFID        26..47
FT                   /evidence="ECO:0000250"
FT   DISULFID        33..56
FT                   /evidence="ECO:0000250"
FT   DISULFID        37..58
FT                   /evidence="ECO:0000250"
FT   CONFLICT        13
FT                   /note="L -> P (in Ref. 2; AAK57517)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        17
FT                   /note="R -> G (in Ref. 2; AAK57517)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   61 AA;  6747 MW;  B4FF9E1707E9148B CRC64;
     MTYAILIIVS LLLISDRISN VVDKYCSENP LDCNEHCLKT KNQIGICHGA NGNEKCSCME
     S