ID   DENR_ASHGO              Reviewed;         199 AA.
AC   Q75CN1;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Translation machinery-associated protein 22;
GN   Name=TMA22; OrderedLocusNames=ACL112C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- SUBUNIT: Interacts with the 40S ribosomal subunit. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- DOMAIN: The SUI1 domain may be involved in RNA binding.
CC   -!- SIMILARITY: Belongs to the DENR family. {ECO:0000305}.
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DR   EMBL; AE016816; AAS51116.1; -; Genomic_DNA.
DR   RefSeq; NP_983292.1; NM_208645.1.
DR   AlphaFoldDB; Q75CN1; -.
DR   SMR; Q75CN1; -.
DR   STRING; 33169.AAS51116; -.
DR   PRIDE; Q75CN1; -.
DR   EnsemblFungi; AAS51116; AAS51116; AGOS_ACL112C.
DR   GeneID; 4619412; -.
DR   KEGG; ago:AGOS_ACL112C; -.
DR   eggNOG; KOG3239; Eukaryota.
DR   HOGENOM; CLU_073511_0_1_1; -.
DR   InParanoid; Q75CN1; -.
DR   OMA; VIYCGVC; -.
DR   Proteomes; UP000000591; Chromosome III.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IBA:GO_Central.
DR   GO; GO:0002188; P:translation reinitiation; IBA:GO_Central.
DR   InterPro; IPR005873; DENR_eukaryotes.
DR   InterPro; IPR001950; SUI1.
DR   InterPro; IPR036877; SUI1_dom_sf.
DR   Pfam; PF01253; SUI1; 1.
DR   SUPFAM; SSF55159; SSF55159; 1.
DR   TIGRFAMs; TIGR01159; DRP1; 1.
DR   PROSITE; PS50296; SUI1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..199
FT                   /note="Translation machinery-associated protein 22"
FT                   /id="PRO_0000320432"
FT   DOMAIN          97..168
FT                   /note="SUI1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00200"
SQ   SEQUENCE   199 AA;  22543 MW;  02433AB5F7F94F9C CRC64;
     MLKKVVYCGV CSLPPEYCEF TGKIRRCKVW LHEHDQELFA QLYGDDKEDV DGVAARLGQS
     SIGEEREEQL EKKLQKLQAR EESKEQRELA RKLSSRVVIR REARTKRKCM VVVAGLEVFE
     IDMKKLAKTF ASKFATGCSV SKNVEKKEEV VVQGDIADEV EAYIHALLEE KGMKGVKVEQ
     IDAAKKKKKT PTTTTPPPS