ID   DENR_CHICK              Reviewed;         198 AA.
AC   Q5ZJ39;
DT   24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Density-regulated protein;
DE            Short=DRP;
GN   Name=DENR; ORFNames=RCJMB04_20p1;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: May be involved in the translation of target mRNAs by
CC       scanning and recognition of the initiation codon. Involved in
CC       translation initiation; promotes recruitment of aminoacetyled initiator
CC       tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA
CC       and mRNA from recycled 40S subunits following ABCE1-mediated
CC       dissociation of post-termination ribosomal complexes into subunits (By
CC       similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DENR family. {ECO:0000305}.
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DR   EMBL; AJ720595; CAG32254.1; -; mRNA.
DR   RefSeq; NP_001072973.1; NM_001079505.1.
DR   AlphaFoldDB; Q5ZJ39; -.
DR   SMR; Q5ZJ39; -.
DR   STRING; 9031.ENSGALP00000033977; -.
DR   PaxDb; Q5ZJ39; -.
DR   Ensembl; ENSGALT00000053318; ENSGALP00000046415; ENSGALG00000003795.
DR   GeneID; 771794; -.
DR   KEGG; gga:771794; -.
DR   CTD; 8562; -.
DR   VEuPathDB; HostDB:geneid_771794; -.
DR   eggNOG; KOG3239; Eukaryota.
DR   GeneTree; ENSGT00390000014349; -.
DR   HOGENOM; CLU_073511_1_0_1; -.
DR   InParanoid; Q5ZJ39; -.
DR   OMA; VIYCGVC; -.
DR   OrthoDB; 1490022at2759; -.
DR   PhylomeDB; Q5ZJ39; -.
DR   PRO; PR:Q5ZJ39; -.
DR   Proteomes; UP000000539; Chromosome 15.
DR   Bgee; ENSGALG00000003795; Expressed in spermatid and 14 other tissues.
DR   ExpressionAtlas; Q5ZJ39; baseline and differential.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IBA:GO_Central.
DR   GO; GO:0002188; P:translation reinitiation; IBA:GO_Central.
DR   InterPro; IPR005873; DENR_eukaryotes.
DR   InterPro; IPR001950; SUI1.
DR   InterPro; IPR036877; SUI1_dom_sf.
DR   Pfam; PF01253; SUI1; 1.
DR   SUPFAM; SSF55159; SSF55159; 1.
DR   TIGRFAMs; TIGR01159; DRP1; 1.
DR   PROSITE; PS50296; SUI1; 1.
PE   2: Evidence at transcript level;
KW   Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..198
FT                   /note="Density-regulated protein"
FT                   /id="PRO_0000130603"
FT   DOMAIN          115..182
FT                   /note="SUI1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00200"
FT   REGION          72..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   198 AA;  22158 MW;  2A43A2FF5D6EC9C4 CRC64;
     MATDVAEPVV PDCRGDIRSG ARSDADYPLR VLYCGVCSLP TEYCEYMPDV TKCRQWLEKN
     FPDEFAKLTV ENSPKQEAGV GEGQGTAGEE EEKKKQKRGG RGQIKQKKKT VPQKVTIAKI
     PRAKKKYVTR VCGLATFEID LKEAQRFFAQ KFSCGASVTG EDEIIIQGDF TDDIIDVIQE
     KWPEVDDDSI EDLGEVKK