DENR_DICDI
ID DENR_DICDI Reviewed; 224 AA.
AC Q54WG0;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 77.
DE RecName: Full=Density-regulated protein homolog;
GN Name=denr; ORFNames=DDB_G0279677;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SIMILARITY: Belongs to the DENR family. {ECO:0000305}.
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DR EMBL; AAFI02000032; EAL67613.1; -; Genomic_DNA.
DR RefSeq; XP_641593.1; XM_636501.1.
DR AlphaFoldDB; Q54WG0; -.
DR SMR; Q54WG0; -.
DR STRING; 44689.DDB0266779; -.
DR PaxDb; Q54WG0; -.
DR EnsemblProtists; EAL67613; EAL67613; DDB_G0279677.
DR GeneID; 8622167; -.
DR KEGG; ddi:DDB_G0279677; -.
DR dictyBase; DDB_G0279677; denr.
DR eggNOG; KOG3239; Eukaryota.
DR HOGENOM; CLU_073511_0_1_1; -.
DR InParanoid; Q54WG0; -.
DR OMA; VIYCGVC; -.
DR PhylomeDB; Q54WG0; -.
DR PRO; PR:Q54WG0; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR GO; GO:0001731; P:formation of translation preinitiation complex; IBA:GO_Central.
DR GO; GO:0002188; P:translation reinitiation; IBA:GO_Central.
DR InterPro; IPR001950; SUI1.
DR InterPro; IPR036877; SUI1_dom_sf.
DR Pfam; PF01253; SUI1; 1.
DR SUPFAM; SSF55159; SSF55159; 1.
DR PROSITE; PS50296; SUI1; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..224
FT /note="Density-regulated protein homolog"
FT /id="PRO_0000322641"
FT DOMAIN 131..204
FT /note="SUI1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00200"
FT REGION 35..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..124
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 224 AA; 24747 MW; 194B6C62345AE4A7 CRC64;
MSDTESSTPS QPIVVVEYCK ICSLPTEYCE YGPSAKQCLK ENGPHPNNNK NTASGKDSSN
TTATTTTTDT TTTTTTSTEN TEEKLKDLKI VDDSKEVSHV DAGKSESKEA TGEEKEKEKV
SKKKKEVKPQ IIIEVNQRNK RKHVTKITGL ELYGIKLSDA AKVMAKKFSC GCSVVKSISN
PNSEDIDIQG DFGEELVDLI EEKYPTVPLS EIYFLEDKKK VKAR
