ID   DENR_PICGU              Reviewed;         201 AA.
AC   A5DGV3;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Translation machinery-associated protein 22;
GN   Name=TMA22; ORFNames=PGUG_02504;
OS   Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS   / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX   NCBI_TaxID=294746;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- SUBUNIT: Interacts with the 40S ribosomal subunit. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- DOMAIN: The SUI1 domain may be involved in RNA binding.
CC   -!- SIMILARITY: Belongs to the DENR family. {ECO:0000305}.
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DR   EMBL; CH408157; EDK38406.1; -; Genomic_DNA.
DR   RefSeq; XP_001484775.1; XM_001484725.1.
DR   AlphaFoldDB; A5DGV3; -.
DR   SMR; A5DGV3; -.
DR   STRING; 4929.XP_001484775.1; -.
DR   EnsemblFungi; EDK38406; EDK38406; PGUG_02504.
DR   GeneID; 5126840; -.
DR   KEGG; pgu:PGUG_02504; -.
DR   eggNOG; KOG3239; Eukaryota.
DR   HOGENOM; CLU_073511_0_1_1; -.
DR   InParanoid; A5DGV3; -.
DR   OMA; VIYCGVC; -.
DR   OrthoDB; 1490022at2759; -.
DR   Proteomes; UP000001997; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR   InterPro; IPR005873; DENR_eukaryotes.
DR   InterPro; IPR001950; SUI1.
DR   InterPro; IPR036877; SUI1_dom_sf.
DR   Pfam; PF01253; SUI1; 1.
DR   SUPFAM; SSF55159; SSF55159; 1.
DR   TIGRFAMs; TIGR01159; DRP1; 1.
DR   PROSITE; PS50296; SUI1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..201
FT                   /note="Translation machinery-associated protein 22"
FT                   /id="PRO_0000320448"
FT   DOMAIN          94..165
FT                   /note="SUI1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00200"
SQ   SEQUENCE   201 AA;  22626 MW;  8C90486BDBC57DA1 CRC64;
     MTEVEPKSVL YCGVCSFPPE FCEFGGSFKR CKEWLEQNDK ELYEKLYSED ALANATSTLS
     IDKEQKIAKE LEKKQAKEEA KQERELKKQL ASKVTIKRIE RNKRKHVIAI SGLEVFDIDM
     KKLSKTFASK FATGASVTKN AEKKDEIIVQ GDVSDEARAY IEKLLEEKGL NEVKVEQIDD
     KKKKKAAEAA EAAAAATGNK K