ID   DENR_SCHPO              Reviewed;         190 AA.
AC   O42929;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 119.
DE   RecName: Full=Translation machinery-associated protein 22;
DE   AltName: Full=Density-regulated protein homolog;
GN   Name=tma22; ORFNames=SPBC16C6.05;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- SUBUNIT: Interacts with the 40S ribosomal subunit. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- DOMAIN: The SUI1 domain may be involved in RNA binding.
CC   -!- SIMILARITY: Belongs to the DENR family. {ECO:0000305}.
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DR   EMBL; CU329671; CAA16913.1; -; Genomic_DNA.
DR   PIR; T39556; T39556.
DR   RefSeq; NP_596803.1; NM_001023824.2.
DR   AlphaFoldDB; O42929; -.
DR   SMR; O42929; -.
DR   BioGRID; 276690; 84.
DR   STRING; 4896.SPBC16C6.05.1; -.
DR   MaxQB; O42929; -.
DR   PaxDb; O42929; -.
DR   EnsemblFungi; SPBC16C6.05.1; SPBC16C6.05.1:pep; SPBC16C6.05.
DR   GeneID; 2540154; -.
DR   KEGG; spo:SPBC16C6.05; -.
DR   PomBase; SPBC16C6.05; tma22.
DR   VEuPathDB; FungiDB:SPBC16C6.05; -.
DR   eggNOG; KOG3239; Eukaryota.
DR   HOGENOM; CLU_073511_0_1_1; -.
DR   InParanoid; O42929; -.
DR   OMA; VIYCGVC; -.
DR   PhylomeDB; O42929; -.
DR   PRO; PR:O42929; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0022626; C:cytosolic ribosome; ISO:PomBase.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IBA:GO_Central.
DR   GO; GO:0002188; P:translation reinitiation; IBA:GO_Central.
DR   InterPro; IPR005873; DENR_eukaryotes.
DR   InterPro; IPR001950; SUI1.
DR   InterPro; IPR036877; SUI1_dom_sf.
DR   Pfam; PF01253; SUI1; 1.
DR   SUPFAM; SSF55159; SSF55159; 1.
DR   TIGRFAMs; TIGR01159; DRP1; 1.
DR   PROSITE; PS50296; SUI1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..190
FT                   /note="Translation machinery-associated protein 22"
FT                   /id="PRO_0000130608"
FT   DOMAIN          99..170
FT                   /note="SUI1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00200"
FT   REGION          63..83
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   190 AA;  21633 MW;  391D69E6C3CD642D CRC64;
     MASQTIPKLK SVLYCDVCTL PVEYCEFEGT LKKCKEWLKS SHPDVYDKLY GEQDLSKDLE
     NTLNVSGTKD SNAEEQPAKL TKEEKRVERE EAKRMASKVL IKTIERTKRK RVTTVQGLDA
     FGIETKKAAK MLANKFATGA SVTKTADKKD EIVVQGDLNY DIFDFILEKF KEVPEDNIKI
     VEDTKSKKKQ