DENR_VANPO
ID DENR_VANPO Reviewed; 206 AA.
AC A7TES6;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-OCT-2007, sequence version 1.
DT 25-MAY-2022, entry version 60.
DE RecName: Full=Translation machinery-associated protein 22;
GN Name=TMA22; ORFNames=Kpol_1050p29;
OS Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX NCBI_TaxID=436907;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC Y-8283 / UCD 57-17;
RX PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT species descended from a whole-genome duplication.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC -!- SUBUNIT: Interacts with the 40S ribosomal subunit. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- DOMAIN: The SUI1 domain may be involved in RNA binding.
CC -!- SIMILARITY: Belongs to the DENR family. {ECO:0000305}.
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DR EMBL; DS480381; EDO19172.1; -; Genomic_DNA.
DR RefSeq; XP_001647030.1; XM_001646980.1.
DR AlphaFoldDB; A7TES6; -.
DR SMR; A7TES6; -.
DR STRING; 436907.A7TES6; -.
DR EnsemblFungi; EDO19172; EDO19172; Kpol_1050p29.
DR GeneID; 5547503; -.
DR KEGG; vpo:Kpol_1050p29; -.
DR eggNOG; KOG3239; Eukaryota.
DR HOGENOM; CLU_073511_0_1_1; -.
DR InParanoid; A7TES6; -.
DR OMA; VIYCGVC; -.
DR OrthoDB; 1490022at2759; -.
DR PhylomeDB; A7TES6; -.
DR Proteomes; UP000000267; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR InterPro; IPR005873; DENR_eukaryotes.
DR InterPro; IPR001950; SUI1.
DR InterPro; IPR036877; SUI1_dom_sf.
DR Pfam; PF01253; SUI1; 1.
DR SUPFAM; SSF55159; SSF55159; 1.
DR TIGRFAMs; TIGR01159; DRP1; 1.
DR PROSITE; PS50296; SUI1; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..206
FT /note="Translation machinery-associated protein 22"
FT /id="PRO_0000320450"
FT DOMAIN 98..169
FT /note="SUI1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00200"
FT REGION 184..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 206 AA; 23467 MW; 98DDBFC5E14914BA CRC64;
MLQEVVYCGI CSYPPEYCEF SGKLKRCKVW LSENDTELYA KLYGNEIDEE VANAANKLGS
SSIGEAREEK LEKDLLRLQA KQENREQREL AKKLSSKVVI KREARTKRKF IVAISGLEVF
EIDMKKLAKT FASKFATGCS VSKNAEKKDE IVIQGDVLEE VEKYIHSLLE EKGLKNVKLE
IIDSQKKKKK PTDEANSNNN NNNNNK