ID   DENR_XENTR              Reviewed;         200 AA.
AC   Q6DFN7; Q28I35;
DT   24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Density-regulated protein;
DE            Short=DRP;
GN   Name=denr; ORFNames=TEgg137c20.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in the translation of target mRNAs by
CC       scanning and recognition of the initiation codon. Involved in
CC       translation initiation; promotes recruitment of aminoacetyled initiator
CC       tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA
CC       and mRNA from recycled 40S subunits following ABCE1-mediated
CC       dissociation of post-termination ribosomal complexes into subunits (By
CC       similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DENR family. {ECO:0000305}.
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DR   EMBL; CR760613; CAJ81326.1; -; mRNA.
DR   EMBL; BC076697; AAH76697.1; -; mRNA.
DR   EMBL; BC087985; AAH87985.1; -; mRNA.
DR   RefSeq; NP_001006814.1; NM_001006813.1.
DR   RefSeq; XP_012815419.1; XM_012959965.2.
DR   AlphaFoldDB; Q6DFN7; -.
DR   SMR; Q6DFN7; -.
DR   STRING; 8364.ENSXETP00000061854; -.
DR   PaxDb; Q6DFN7; -.
DR   DNASU; 448530; -.
DR   Ensembl; ENSXETT00000063343; ENSXETP00000061854; ENSXETG00000005791.
DR   GeneID; 448530; -.
DR   KEGG; xtr:448530; -.
DR   CTD; 8562; -.
DR   Xenbase; XB-GENE-1002798; denr.
DR   eggNOG; KOG3239; Eukaryota.
DR   HOGENOM; CLU_073511_1_0_1; -.
DR   InParanoid; Q6DFN7; -.
DR   OMA; VIYCGVC; -.
DR   OrthoDB; 1490022at2759; -.
DR   PhylomeDB; Q6DFN7; -.
DR   TreeFam; TF105912; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000005791; Expressed in testis and 16 other tissues.
DR   ExpressionAtlas; Q6DFN7; differential.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IBA:GO_Central.
DR   GO; GO:0002188; P:translation reinitiation; IBA:GO_Central.
DR   InterPro; IPR005873; DENR_eukaryotes.
DR   InterPro; IPR001950; SUI1.
DR   InterPro; IPR036877; SUI1_dom_sf.
DR   Pfam; PF01253; SUI1; 1.
DR   SUPFAM; SSF55159; SSF55159; 1.
DR   TIGRFAMs; TIGR01159; DRP1; 1.
DR   PROSITE; PS50296; SUI1; 1.
PE   2: Evidence at transcript level;
KW   Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..200
FT                   /note="Density-regulated protein"
FT                   /id="PRO_0000130606"
FT   DOMAIN          117..184
FT                   /note="SUI1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00200"
FT   REGION          78..112
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   200 AA;  22359 MW;  066E99576E3EFEEF CRC64;
     MASIAIENAE PVPSDCKGDL KISKFDGDLP LKVLYCGVCS LPTEYCEYMP DVAKCRQWLE
     KNFPDEFSKL TLGISPKQET GTVEGQATSG EEEEKKKQKR GGRGQIKQKK KTVPQKVTIA
     KIPRAKKKYV TRVCGLATFE IELKDAQRFF AQKFSCGASV TGEDEIIIQG DFTDDIIDVI
     QEKWPEVDDD SIEDLGEVKK