ID   DENR_YEAS7              Reviewed;         198 AA.
AC   A6ZPY2;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Translation machinery-associated protein 22;
DE   AltName: Full=Density-regulated protein homolog;
GN   Name=TMA22; Synonyms=RBF22; ORFNames=SCY_2943;
OS   Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=307796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJM789;
RX   PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA   Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA   Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA   Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA   Steinmetz L.M.;
RT   "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT   strain YJM789.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC   -!- SUBUNIT: Interacts with the 40S ribosomal subunit. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- DOMAIN: The SUI1 domain may be involved in RNA binding.
CC   -!- SIMILARITY: Belongs to the DENR family. {ECO:0000305}.
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DR   EMBL; AAFW02000040; EDN63342.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6ZPY2; -.
DR   SMR; A6ZPY2; -.
DR   IntAct; A6ZPY2; 2.
DR   MINT; A6ZPY2; -.
DR   PRIDE; A6ZPY2; -.
DR   EnsemblFungi; EDN63342; EDN63342; SCY_2943.
DR   HOGENOM; CLU_073511_0_1_1; -.
DR   Proteomes; UP000007060; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR   InterPro; IPR005873; DENR_eukaryotes.
DR   InterPro; IPR001950; SUI1.
DR   InterPro; IPR036877; SUI1_dom_sf.
DR   Pfam; PF01253; SUI1; 1.
DR   SUPFAM; SSF55159; SSF55159; 1.
DR   TIGRFAMs; TIGR01159; DRP1; 1.
DR   PROSITE; PS50296; SUI1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..198
FT                   /note="Translation machinery-associated protein 22"
FT                   /id="PRO_0000320452"
FT   DOMAIN          99..170
FT                   /note="SUI1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00200"
SQ   SEQUENCE   198 AA;  22495 MW;  778A38A6BD28E40C CRC64;
     MLREVIYCGI CSYPPEYCEF SGKLKRCKVW LSENHADLYA KLYGTDDNTQ EVEAVTNKLA
     ESSIGEAREE KLEKDLLKIQ KKQENREQRE LAKKLSSKVI IKREARTKRK FIVAISGLEV
     FDIDMKKLAK TFASRFATGC SVSKNAEKKE EVVIQGDVMD EVETYIHSLL EEKGLKDVKV
     ETIDAKKKKK PAAEGAAK