ACYP_NOCFA
ID ACYP_NOCFA Reviewed; 100 AA.
AC Q5YS19;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 25-MAY-2022, entry version 95.
DE RecName: Full=Acylphosphatase;
DE EC=3.6.1.7;
DE AltName: Full=Acylphosphate phosphohydrolase;
GN Name=acyP; OrderedLocusNames=NFA_41730;
OS Nocardia farcinica (strain IFM 10152).
OC Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae; Nocardia.
OX NCBI_TaxID=247156;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFM 10152;
RX PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA Shiba T., Hattori M.;
RT "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=an acyl phosphate + H2O = a carboxylate + H(+) + phosphate;
CC Xref=Rhea:RHEA:14965, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:29067, ChEBI:CHEBI:43474, ChEBI:CHEBI:59918; EC=3.6.1.7;
CC -!- SIMILARITY: Belongs to the acylphosphatase family. {ECO:0000305}.
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DR EMBL; AP006618; BAD59022.1; -; Genomic_DNA.
DR RefSeq; WP_011210707.1; NC_006361.1.
DR AlphaFoldDB; Q5YS19; -.
DR SMR; Q5YS19; -.
DR STRING; 247156.NFA_41730; -.
DR EnsemblBacteria; BAD59022; BAD59022; NFA_41730.
DR GeneID; 61134809; -.
DR KEGG; nfa:NFA_41730; -.
DR eggNOG; COG1254; Bacteria.
DR HOGENOM; CLU_141932_3_0_11; -.
DR OMA; FRWWTRA; -.
DR Proteomes; UP000006820; Chromosome.
DR GO; GO:0003998; F:acylphosphatase activity; IEA:UniProtKB-EC.
DR InterPro; IPR020456; Acylphosphatase.
DR InterPro; IPR001792; Acylphosphatase-like_dom.
DR InterPro; IPR036046; Acylphosphatase-like_dom_sf.
DR InterPro; IPR017968; Acylphosphatase_CS.
DR PANTHER; PTHR47268; PTHR47268; 1.
DR Pfam; PF00708; Acylphosphatase; 1.
DR SUPFAM; SSF54975; SSF54975; 1.
DR PROSITE; PS00150; ACYLPHOSPHATASE_1; 1.
DR PROSITE; PS00151; ACYLPHOSPHATASE_2; 1.
DR PROSITE; PS51160; ACYLPHOSPHATASE_3; 1.
PE 3: Inferred from homology;
KW Hydrolase; Reference proteome.
FT CHAIN 1..100
FT /note="Acylphosphatase"
FT /id="PRO_0000326760"
FT DOMAIN 14..100
FT /note="Acylphosphatase-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00520"
FT ACT_SITE 29
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00520"
FT ACT_SITE 47
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00520"
SQ SEQUENCE 100 AA; 11155 MW; 4BFF5D9F2A57306F CRC64;
MSESPHDHAG DPVRLSAWVH GHVQGVGFRW WTRSRALESG LTGYARNAPD GRVHVIAEGP
RERCERLLEL LRSGTTPGRV SLVVESWEPA RGDLTGFEER
