ID   3BP5L_XENLA             Reviewed;         373 AA.
AC   Q5U584;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=SH3 domain-binding protein 5-like;
DE            Short=SH3BP-5-like;
GN   Name=sh3bp5l;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Functions as guanine nucleotide exchange factor (GEF) for
CC       rab11a. {ECO:0000250|UniProtKB:Q7L8J4}.
CC   -!- SIMILARITY: Belongs to the SH3BP5 family. {ECO:0000305}.
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DR   EMBL; BC084800; AAH84800.1; -; mRNA.
DR   RefSeq; NP_001088473.1; NM_001095004.1.
DR   RefSeq; XP_018084601.1; XM_018229112.1.
DR   RefSeq; XP_018084602.1; XM_018229113.1.
DR   RefSeq; XP_018084603.1; XM_018229114.1.
DR   RefSeq; XP_018084604.1; XM_018229115.1.
DR   RefSeq; XP_018084605.1; XM_018229116.1.
DR   RefSeq; XP_018084606.1; XM_018229117.1.
DR   RefSeq; XP_018084607.1; XM_018229118.1.
DR   AlphaFoldDB; Q5U584; -.
DR   SMR; Q5U584; -.
DR   DNASU; 495338; -.
DR   GeneID; 495338; -.
DR   KEGG; xla:495338; -.
DR   CTD; 495338; -.
DR   Xenbase; XB-GENE-920572; sh3bp5l.L.
DR   OMA; IRSEREH; -.
DR   OrthoDB; 566222at2759; -.
DR   Proteomes; UP000186698; Chromosome 8L.
DR   Bgee; 495338; Expressed in muscle tissue and 19 other tissues.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   InterPro; IPR007940; SH3BP5.
DR   PANTHER; PTHR19423; PTHR19423; 2.
DR   Pfam; PF05276; SH3BP5; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Guanine-nucleotide releasing factor; Reference proteome.
FT   CHAIN           1..373
FT                   /note="SH3 domain-binding protein 5-like"
FT                   /id="PRO_0000317511"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          274..308
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          332..373
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          35..98
FT                   /evidence="ECO:0000255"
FT   COILED          170..258
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        347..365
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   373 AA;  41591 MW;  C2994E1E58176600 CRC64;
     MEGKEGPPCE VRLPTPGAER EGPVHPELGA FGESASDAIK LSETSNDAKK EEIEEELDPR
     IQEELERLNQ ASEEINLLEL QLDEARTAYR RILTESARRL NGLATQLGAC IDKARPYYEA
     RRLAKEAQQD THSAALRYER AVSMHAAARE MVFVAEQGVT ADKNRLDPTW QEMLNHATCK
     VNEAEEERLR SEFEHQRVTR LCHEAEAKVQ TLQKSLKRLI IKSRPYFELK AQLNTILEEH
     KSRVTLLENS VAQAKLRYSG TLHNLEKISE EIHARRTQSS VLSQRAPPLG AEAPPSVKDG
     ETGPPADTVS LLSLQTIASD LQKSDSVEHL RDLTDVTSLD GRETGAVESG GSRERGEDRG
     TGGAFRHHRS VSL