DEP1_ORYSJ
ID DEP1_ORYSJ Reviewed; 426 AA.
AC Q67UU9; A0A5S6R9V4; Q0J1G4;
DT 29-SEP-2021, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Guanine nucleotide-binding protein subunit gamma 4 {ECO:0000305};
DE AltName: Full=Heterotrimeric G protein gamma-subunit 4 {ECO:0000303|PubMed:30441812};
DE AltName: Full=OsGGC3 {ECO:0000305};
DE AltName: Full=Protein DENSE AND ERECT PANICLE 1 {ECO:0000303|PubMed:19305410};
DE AltName: Full=Protein ERECT POSE {ECO:0000303|PubMed:19407986};
GN Name=DEP1 {ECO:0000303|PubMed:19305410};
GN Synonyms=DN1 {ECO:0000303|Ref.2}, EP {ECO:0000303|PubMed:19407986},
GN qPE9-1 {ECO:0000303|PubMed:19546322}, RGG4 {ECO:0000303|PubMed:30441812};
GN OrderedLocusNames=Os09g0441900 {ECO:0000312|EMBL:BAT08302.1},
GN LOC_Os09g36160;
GN ORFNames=OsJ_29530 {ECO:0000312|EMBL:EEE69800.1},
GN P0046G12.12-1 {ECO:0000312|EMBL:BAD38070.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], FUNCTION, SUBCELLULAR LOCATION,
RP TISSUE SPECIFICITY, AND DISRUPTION PHENOTYPE.
RX PubMed=19305410; DOI=10.1038/ng.352;
RA Huang X., Qian Q., Liu Z., Sun H., He S., Luo D., Xia G., Chu C., Li J.,
RA Fu X.;
RT "Natural variation at the DEP1 locus enhances grain yield in rice.";
RL Nat. Genet. 41:494-497(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], SUBCELLULAR LOCATION, AND
RP DISRUPTION PHENOTYPE.
RC TISSUE=Shoot;
RX DOI=10.1270/jsbbs.61.17;
RA Taguchi-Shiobara F., Kawagoe Y., Kato H., Onodera H., Tagiri A., Hara N.,
RA Miyao A., Hirochika H., Kitano H., Yano M., Toki S.;
RT "A loss-of-function mutation of rice DENSE PANICLE 1 causes semi-dwarfness
RT and slightly increased number of spikelets.";
RL Breed. Sci. 61:17-25(2011).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP FUNCTION.
RX PubMed=19546322; DOI=10.1534/genetics.109.102681;
RA Zhou Y., Zhu J., Li Z., Yi C., Liu J., Zhang H., Tang S., Gu M., Liang G.;
RT "Deletion in a quantitative trait gene qPE9-1 associated with panicle
RT erectness improves plant architecture during rice domestication.";
RL Genetics 183:315-324(2009).
RN [8]
RP FUNCTION.
RX PubMed=19407986; DOI=10.1007/s00122-009-1019-0;
RA Wang J., Nakazaki T., Chen S., Chen W., Saito H., Tsukiyama T., Okumoto Y.,
RA Xu Z., Tanisaka T.;
RT "Identification and characterization of the erect-pose panicle gene EP
RT conferring high grain yield in rice (Oryza sativa L.).";
RL Theor. Appl. Genet. 119:85-91(2009).
RN [9]
RP FUNCTION.
RX PubMed=24163402; DOI=10.1093/jxb/ert267;
RA Kunihiro S., Saito T., Matsuda T., Inoue M., Kuramata M.,
RA Taguchi-Shiobara F., Youssefian S., Berberich T., Kusano T.;
RT "Rice DEP1, encoding a highly cysteine-rich G protein gamma subunit,
RT confers cadmium tolerance on yeast cells and plants.";
RL J. Exp. Bot. 64:4517-4527(2013).
RN [10]
RP IDENTIFICATION BY MASS SPECTROMETRY, SUBUNIT, AND SUBCELLULAR LOCATION.
RX PubMed=30441812; DOI=10.3390/ijms19113596;
RA Matsuta S., Nishiyama A., Chaya G., Itoh T., Miura K., Iwasaki Y.;
RT "Characterization of heterotrimeric G protein gamma4 subunit in rice.";
RL Int. J. Mol. Sci. 19:0-0(2018).
RN [11]
RP FUNCTION.
RX PubMed=29487318; DOI=10.1038/s41467-018-03141-y;
RA Sun S., Wang L., Mao H., Shao L., Li X., Xiao J., Ouyang Y., Zhang Q.;
RT "A G-protein pathway determines grain size in rice.";
RL Nat. Commun. 9:851-851(2018).
RN [12]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=32111163; DOI=10.1186/s12870-020-2289-6;
RA Cui Y., Jiang N., Xu Z., Xu Q.;
RT "Heterotrimeric G protein are involved in the regulation of multiple
RT agronomic traits and stress tolerance in rice.";
RL BMC Plant Biol. 20:90-90(2020).
CC -!- FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved
CC as a modulator or transducer in various transmembrane signaling systems
CC (Probable). The beta and gamma chains are required for the GTPase
CC activity, for replacement of GDP by GTP, and for G protein-effector
CC interaction (Probable). Involved in the regulation of plant
CC architecture, panicle erectness, panicle and grain length, grain
CC weight, and grain yield (PubMed:19305410, PubMed:19407986,
CC PubMed:19546322). Involved in the regulation of grain size
CC (PubMed:29487318, PubMed:32111163). {ECO:0000269|PubMed:19305410,
CC ECO:0000269|PubMed:19407986, ECO:0000269|PubMed:19546322,
CC ECO:0000269|PubMed:29487318, ECO:0000269|PubMed:32111163,
CC ECO:0000305|PubMed:29487318}.
CC -!- SUBUNIT: G proteins are composed of 3 units, alpha, beta and gamma.
CC {ECO:0000305|PubMed:30441812}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:19305410,
CC ECO:0000269|Ref.2}. Cell membrane {ECO:0000269|PubMed:30441812,
CC ECO:0000269|Ref.2}.
CC -!- TISSUE SPECIFICITY: Expressed in the inflorescence meristem and
CC intercalary meristem (PubMed:19305410). Expressed in the bract
CC primordia of primary and secondary rachis branches (PubMed:19305410).
CC {ECO:0000269|PubMed:19305410}.
CC -!- DISRUPTION PHENOTYPE: Semi-dwarf phenotype (PubMed:19305410, Ref.2).
CC Dense and erect panicles, and high grain number per panicle
CC (PubMed:19305410, PubMed:32111163). Increased number of spikelets
CC (Ref.2). Increased tolerance to drought, salt and cold stresses
CC (PubMed:32111163). {ECO:0000269|PubMed:19305410,
CC ECO:0000269|PubMed:32111163, ECO:0000269|Ref.2}.
CC -!- MISCELLANEOUS: Involved in tolerance to cadmium and copper ions
CC (PubMed:24163402). Seedlings overexpressing DEP1 exhibit enhanced
CC tolerance to cadmium (PubMed:24163402). {ECO:0000269|PubMed:24163402}.
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DR EMBL; FJ039904; ACI25446.1; -; Genomic_DNA.
DR EMBL; FJ039905; ACI25447.1; -; mRNA.
DR EMBL; AB475006; BAI66276.1; -; Genomic_DNA.
DR EMBL; AB475007; BAI66277.1; -; mRNA.
DR EMBL; AP005419; BAD38070.1; -; Genomic_DNA.
DR EMBL; AP008215; BAF25201.2; -; Genomic_DNA.
DR EMBL; AP014965; BAT08302.1; -; Genomic_DNA.
DR EMBL; CM000146; EEE69800.1; -; Genomic_DNA.
DR RefSeq; XP_015610892.1; XM_015755406.1.
DR AlphaFoldDB; Q67UU9; -.
DR STRING; 4530.OS09T0441900-01; -.
DR PaxDb; Q67UU9; -.
DR PRIDE; Q67UU9; -.
DR EnsemblPlants; Os09t0441900-01; Os09t0441900-01; Os09g0441900.
DR GeneID; 4347178; -.
DR Gramene; Os09t0441900-01; Os09t0441900-01; Os09g0441900.
DR KEGG; osa:4347178; -.
DR eggNOG; ENOG502RZC5; Eukaryota.
DR HOGENOM; CLU_044537_0_0_1; -.
DR InParanoid; Q67UU9; -.
DR OMA; PSCGCNG; -.
DR OrthoDB; 1551562at2759; -.
DR PlantReactome; R-OSA-9035605; Regulation of seed size.
DR Proteomes; UP000000763; Chromosome 9.
DR Proteomes; UP000007752; Chromosome 9.
DR Proteomes; UP000059680; Chromosome 9.
DR ExpressionAtlas; Q67UU9; baseline and differential.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0005886; C:plasma membrane; IDA:UniProtKB.
DR GO; GO:0048450; P:floral organ structural organization; IMP:UniProtKB.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; TAS:UniProtKB.
DR GO; GO:0080050; P:regulation of seed development; IMP:UniProtKB.
PE 1: Evidence at protein level;
KW Cell membrane; Membrane; Nucleus; Reference proteome.
FT CHAIN 1..426
FT /note="Guanine nucleotide-binding protein subunit gamma 4"
FT /id="PRO_0000453485"
FT DOMAIN 24..107
FT /note="G protein gamma"
FT /evidence="ECO:0000255"
SQ SEQUENCE 426 AA; 45210 MW; 06030D89CBBF2A64 CRC64;
MGEEAVVMEA PRPKSPPRYP DLCGRRRMQL EVQILSREIT FLKDELHFLE GAQPVSRSGC
IKEINEFVGT KHDPLIPTKR RRHRSCRLFR WIGSKLCICI SCLCYCCKCS PKCKRPRCLN
CSCSSCCDEP CCKPNCSACC AGSCCSPDCC SCCKPNCSCC KTPSCCKPNC SCSCPSCSSC
CDTSCCKPSC TCFNIFSCFK SLYSCFKIPS CFKSQCNCSS PNCCTCTLPS CSCKGCACPS
CGCNGCGCPS CGCNGCGCPS CGCNGCGLPS CGCNGCGSCS CAQCKPDCGS CSTNCCSCKP
SCNGCCGEQC CRCADCFSCS CPRCSSCFNI FKCSCAGCCS SLCKCPCTTQ CFSCQSSCCK
RQPSCCKCQS SCCEGQPSCC EGHCCSLPKP SCPECSCGCV WSCKNCTEGC RCPRCRNPCC
LSGCLC
