ID   DEPD7_MACFA             Reviewed;         502 AA.
AC   Q95JW3; Q4R3Y6;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=DEP domain-containing protein 7;
GN   Name=DEPDC7; ORFNames=QtsA-10154, QtsA-13250;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC   TISSUE=Testis;
RX   PubMed=12498619; DOI=10.1186/1471-2164-3-36;
RA   Osada N., Hida M., Kusuda J., Tanuma R., Hirata M., Suto Y., Hirai M.,
RA   Terao K., Sugano S., Hashimoto K.;
RT   "Cynomolgus monkey testicular cDNAs for discovery of novel human genes in
RT   the human genome sequence.";
RL   BMC Genomics 3:36-36(2002).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q95JW3-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q95JW3-2; Sequence=VSP_028812, VSP_028813;
CC   -!- SIMILARITY: Belongs to the DEPDC7 family. {ECO:0000305}.
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DR   EMBL; AB070065; BAB63010.1; -; mRNA.
DR   EMBL; AB179129; BAE02180.1; -; mRNA.
DR   AlphaFoldDB; Q95JW3; -.
DR   SMR; Q95JW3; -.
DR   STRING; 9541.XP_005578317.1; -.
DR   eggNOG; ENOG502QW4D; Eukaryota.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000591; DEP_dom.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00610; DEP; 1.
DR   SMART; SM00049; DEP; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50186; DEP; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Reference proteome.
FT   CHAIN           1..502
FT                   /note="DEP domain-containing protein 7"
FT                   /id="PRO_0000307738"
FT   DOMAIN          37..127
FT                   /note="DEP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00066"
FT   VAR_SEQ         1..270
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12498619"
FT                   /id="VSP_028812"
FT   VAR_SEQ         440..502
FT                   /note="YIYCQRIDQRDYSNNTQKTTKDELLNLLKTIDEDSKLSAKEKKKLLGQFYKC
FT                   HPDIFIEHFGD -> NLRNIVFMIFQRQISGVF (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12498619"
FT                   /id="VSP_028813"
SQ   SEQUENCE   502 AA;  57637 MW;  1620A0C3F5E67A1F CRC64;
     MRGLCEFYWQ EFGIKGFSVA QKPFGATYVW SSIINTLQTQ VEVKKRRHRL KRHNDCFVGS
     EAVDVIFSHL IQNKYFGDVD IPRAKVVRVC QALMDYKVFE AIPTKVFGKD KKPTFEDSSC
     SLYRFTTIPN QDSQLGKENK LCSPSRYADA LFKSSDIKSA SLEDLWENLS LKPANSPHVN
     ISATLSPQVI NEVWQEETIG RLLQLVDLPL LDSLLKQQEA VPKVPQSKRQ SDMVNSSNYL
     DRGILKAYSD SQEDEWLSAA IDCLEYLPDQ MVVEISRSFP EQPDRTDLVK ELLFDAIGRY
     YSSREPLLNH LSDVHNGIAE LLVNGKTEIA LEATQLLLKL LDFQNREEFR RLLYFMAVAA
     NPSEFKLQKE SDNRMVVKRI FSKAIVDNKN LSKGKTDLLV LFLMDHQKDV FKIPGTLHKI
     VSVKLMAIQN GRDPNRDAGY IYCQRIDQRD YSNNTQKTTK DELLNLLKTI DEDSKLSAKE
     KKKLLGQFYK CHPDIFIEHF GD