ID   DERI_PECAS              Reviewed;         152 AA.
AC   Q6D8V9;
DT   16-JAN-2019, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=D-erythrulose-4-phosphate isomerase {ECO:0000303|PubMed:29867142};
DE            EC=5.3.1.34 {ECO:0000269|PubMed:29867142};
GN   Name=derI {ECO:0000303|PubMed:29867142};
GN   OrderedLocusNames=ECA0863 {ECO:0000312|EMBL:CAG73775.1};
OS   Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia
OS   carotovora subsp. atroseptica).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=218491;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCRI 1043 / ATCC BAA-672;
RX   PubMed=15263089; DOI=10.1073/pnas.0402424101;
RA   Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J.,
RA   Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K.,
RA   Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J.,
RA   Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Norbertczak H.,
RA   Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S.,
RA   Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K.;
RT   "Genome sequence of the enterobacterial phytopathogen Erwinia carotovora
RT   subsp. atroseptica and characterization of virulence factors.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004).
RN   [2]
RP   FUNCTION, CATALYTIC ACTIVITY, AND PATHWAY.
RX   PubMed=29867142; DOI=10.1038/s41589-018-0067-7;
RA   Carter M.S., Zhang X., Huang H., Bouvier J.T., Francisco B.S.,
RA   Vetting M.W., Al-Obaidi N., Bonanno J.B., Ghosh A., Zallot R.G.,
RA   Andersen H.M., Almo S.C., Gerlt J.A.;
RT   "Functional assignment of multiple catabolic pathways for D-apiose.";
RL   Nat. Chem. Biol. 14:696-705(2018).
CC   -!- FUNCTION: Involved in catabolism of D-apiose. Catalyzes the
CC       isomerization of D-erythrulose 4-phosphate to D-erythrose 4-phosphate.
CC       {ECO:0000269|PubMed:29867142}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrulose 4-phosphate = D-erythrose 4-phosphate;
CC         Xref=Rhea:RHEA:48784, ChEBI:CHEBI:16897, ChEBI:CHEBI:90796;
CC         EC=5.3.1.34; Evidence={ECO:0000269|PubMed:29867142};
CC   -!- PATHWAY: Carbohydrate metabolism. {ECO:0000269|PubMed:29867142}.
CC   -!- SIMILARITY: Belongs to the LacAB/RpiB family. {ECO:0000305}.
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DR   EMBL; BX950851; CAG73775.1; -; Genomic_DNA.
DR   RefSeq; WP_011092466.1; NC_004547.2.
DR   AlphaFoldDB; Q6D8V9; -.
DR   SMR; Q6D8V9; -.
DR   STRING; 218491.ECA0863; -.
DR   EnsemblBacteria; CAG73775; CAG73775; ECA0863.
DR   KEGG; eca:ECA0863; -.
DR   PATRIC; fig|218491.5.peg.864; -.
DR   eggNOG; COG0698; Bacteria.
DR   HOGENOM; CLU_091396_1_2_6; -.
DR   OMA; ETHHANQ; -.
DR   OrthoDB; 1346802at2; -.
DR   BioCyc; MetaCyc:MON-20964; -.
DR   Proteomes; UP000007966; Chromosome.
DR   GO; GO:0016861; F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses; IEA:UniProt.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.1400.10; -; 1.
DR   InterPro; IPR004785; RpiB.
DR   InterPro; IPR003500; RpiB_LacA_LacB.
DR   InterPro; IPR036569; RpiB_LacA_LacB_sf.
DR   Pfam; PF02502; LacAB_rpiB; 1.
DR   PIRSF; PIRSF005384; RpiB_LacA_B; 1.
DR   SUPFAM; SSF89623; SSF89623; 1.
DR   TIGRFAMs; TIGR01120; rpiB; 1.
DR   TIGRFAMs; TIGR00689; rpiB_lacA_lacB; 1.
PE   1: Evidence at protein level;
KW   Carbohydrate metabolism; Isomerase; Reference proteome.
FT   CHAIN           1..152
FT                   /note="D-erythrulose-4-phosphate isomerase"
FT                   /id="PRO_0000446036"
FT   ACT_SITE        67
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250|UniProtKB:P37351"
SQ   SEQUENCE   152 AA;  16359 MW;  3D470F389FF41149 CRC64;
     MLSIAIGADS AAIDLKNTIT DYLQQKGLTV TDYSYDPTGE NPIYPDVAYT LAHAIKDGKH
     QRGILLCGTG IGMCIVANKV NGIRAAQCHD TYSAQRARKS NNAQVIALGA RVIGPELAKE
     IIGAWLDAEF EGGGSAPKVE KIGYYEHQEK HQ