DERL1_ORYSJ
ID DERL1_ORYSJ Reviewed; 242 AA.
AC Q06397; B7FA80; Q75KY2;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 2.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Derlin-1;
DE AltName: Full=18 kDa cold-induced protein;
DE AltName: Full=DER1-like protein 1;
DE AltName: Full=OsDerlin 1-1;
GN Name=DER1; OrderedLocusNames=Os05g0187800, LOC_Os05g09550;
GN ORFNames=B1007D10.4, OJ1097_A12.10,
GN OsJ_17392 {ECO:0000312|EMBL:EEE62589.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16261349; DOI=10.1007/s00438-005-0039-y;
RA Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J.,
RA Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F.,
RA Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.;
RT "A fine physical map of the rice chromosome 5.";
RL Mol. Genet. Genomics 274:337-345(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RG The rice full-length cDNA consortium;
RT "Oryza sativa full length cDNA.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP PARTIAL NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Nipponbare; TISSUE=Seedling;
RX PubMed=16668981; DOI=10.1104/pp.99.3.1146;
RA Binh L.T., Oono K.;
RT "Molecular cloning and characterization of genes related to chilling
RT tolerance in rice.";
RL Plant Physiol. 99:1146-1150(1992).
CC -!- FUNCTION: May be involved in the degradation process of specific
CC misfolded endoplasmic reticulum (ER) luminal proteins. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Seedling shoots and roots.
CC -!- SIMILARITY: Belongs to the derlin family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAS86403.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAV31196.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAA01631.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=BAA01631.1; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
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DR EMBL; AC093954; AAS86403.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC148611; AAV31196.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014961; BAS92615.1; -; Genomic_DNA.
DR EMBL; CM000142; EEE62589.1; -; Genomic_DNA.
DR EMBL; AK243296; BAH01528.1; -; mRNA.
DR EMBL; D10860; BAA01631.1; ALT_SEQ; mRNA.
DR RefSeq; XP_015640689.1; XM_015785203.1.
DR AlphaFoldDB; Q06397; -.
DR SMR; Q06397; -.
DR STRING; 4530.OS05T0187800-01; -.
DR PaxDb; Q06397; -.
DR PRIDE; Q06397; -.
DR EnsemblPlants; Os05t0187800-01; Os05t0187800-01; Os05g0187800.
DR GeneID; 4338013; -.
DR Gramene; Os05t0187800-01; Os05t0187800-01; Os05g0187800.
DR KEGG; osa:4338013; -.
DR eggNOG; KOG0858; Eukaryota.
DR HOGENOM; CLU_051898_5_0_1; -.
DR InParanoid; Q06397; -.
DR OMA; KAFYFPW; -.
DR OrthoDB; 1609512at2759; -.
DR Proteomes; UP000000763; Chromosome 5.
DR Proteomes; UP000007752; Chromosome 5.
DR Proteomes; UP000059680; Chromosome 5.
DR GO; GO:0000839; C:Hrd1p ubiquitin ligase ERAD-L complex; IBA:GO_Central.
DR GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0051787; F:misfolded protein binding; IBA:GO_Central.
DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IBA:GO_Central.
DR GO; GO:0030433; P:ubiquitin-dependent ERAD pathway; IBA:GO_Central.
DR InterPro; IPR007599; DER1.
DR InterPro; IPR035952; Rhomboid-like_sf.
DR Pfam; PF04511; DER1; 1.
DR SUPFAM; SSF144091; SSF144091; 1.
PE 2: Evidence at transcript level;
KW Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..242
FT /note="Derlin-1"
FT /id="PRO_0000079322"
FT TOPO_DOM 1..20
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 21..41
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 42..55
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 56..76
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 77..94
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 95..115
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 116..157
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 158..178
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 179..242
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 242 AA; 27532 MW; B2FA389D950187EF CRC64;
MSSPAEYYNS LPPISKAYGT LCFFATVLCQ LQILNPPFLA LYYPFVFKKF QIWRLFTSFF
FLGKFSINFG IRLLMIARYG VQLEKGAFEK RTADFLWMMI FGAISLLALS AIPFLDIYFL
GVPMVSMLLY VWSREYPNSQ ISMYGLVQLR SFYLPWAMLG LDVIFGSEIL PGLLGILVGH
TYYFLSVLHP LATGKNYLKT PMWVHKIVAR FRIGVQANAP VRPAAANTGS GAFRGRSYRL
SQ
