ID   DERP6_DERPT             Reviewed;          20 AA.
AC   P49277;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Mite allergen Der p 6;
DE            EC=3.4.21.-;
DE   AltName: Full=Allergen Der p VI;
DE   AltName: Full=DP5;
DE   AltName: Allergen=Der p 6;
DE   Flags: Fragment;
GN   Name=DERP6;
OS   Dermatophagoides pteronyssinus (European house dust mite).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Analgoidea;
OC   Pyroglyphidae; Dermatophagoidinae; Dermatophagoides.
OX   NCBI_TaxID=6956;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=8334537; DOI=10.1111/j.1365-2222.1993.tb00343.x;
RA   Yasueda H., Mita H., Akiyama K., Shida T., Ando T., Sugiyama S.,
RA   Yamakawa H.;
RT   "Allergens from Dermatophagoides mites with chymotryptic activity.";
RL   Clin. Exp. Allergy 23:384-390(1993).
CC   -!- FUNCTION: Protease that shows specificity similar to chymotrypsin.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- ALLERGEN: Causes an allergic reaction in human. Common symptoms of mite
CC       allergy are bronchial asthma, allergic rhinitis and conjunctivitis.
CC   -!- SIMILARITY: Belongs to the peptidase S1 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00274}.
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DR   Allergome; 320; Der p 6.
DR   Allergome; 3267; Der p 6.0101.
DR   MEROPS; S01.187; -.
DR   Proteomes; UP000515146; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Allergen; Direct protein sequencing; Hydrolase; Protease;
KW   Reference proteome; Secreted; Serine protease.
FT   CHAIN           1..>20
FT                   /note="Mite allergen Der p 6"
FT                   /id="PRO_0000088714"
FT   DOMAIN          1..>20
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00274"
FT   UNSURE          1
FT   UNSURE          6
FT   UNSURE          10
FT   UNSURE          11
FT   UNSURE          17
FT   NON_TER         20
SQ   SEQUENCE   20 AA;  2084 MW;  26D5F39E06639983 CRC64;
     AIGXQPAAEA EAPFQISLMK