靶标:
H3-4
产品别名:
H3.4; H3/g; H3C16; H3FT; H3t; HIST3H3; H3-4; H3.4 histone, cluster member; H3.4 histone, cluster member; histone H3.1t; H3 clustered histone 16; H3 histone family, member T; H3.4 histone; H3/t; histone 3, H3; histone H3.4; histone cluster 3 H3; 组蛋白H3;
背景信息:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015],