靶标:
Chchd10
产品别名:
1620401E04Rik; AI267078; Ndg2; Chchd10; coiled-coil-helix-coiled-coil-helix domain containing 10; coiled-coil-helix-coiled-coil-helix domain containing 10; coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial; Nur77 downstream gene 2; 卷曲螺旋结构域蛋白CHCHD10;
背景信息:
Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial, also known as Protein N27C7-4 is a protein that in humans is encoded by the CHCHD10 gene. This gene encodes a mitochondrial protein that is enriched at cristae junctions in the intermembrane space. It may play a role in cristae morphology maintenance or oxidative phosphorylation. Mutations in this gene cause frontotemporal dementia and/or amyotrophic lateral sclerosis-2. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7 and 19.