| ID | 蛋白ID | Accession | GN:Name | DE:Name | GeneID |
| 446902 | SIR5A_XENLA | Q5HZN8 | sirt5-a | NAD-dependent protein deacylase sirtuin-5A, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03160}; 2.3.1.- {ECO:0000255|HAMAP-Rule:MF_03160}; Regulatory protein SIR2 homolog 5-a {ECO:0000255|HAMAP-Rule:MF_03160} | 496346 |
| 446901 | SIR4_YEAST | D6VSK9; P11978 | SIR4 | Regulatory protein SIR4; Silent information regulator 4 | 851813 |
| 446900 | SIR4_TRYB2 | D6XL49; Q57YZ9 | SIR2rp2 | NAD-dependent protein deacylase SIR2rp2 {ECO:0000255|HAMAP-Rule:MF_03161}; 2.3.1.286 {ECO:0000255|HAMAP-Rule:MF_03161}; Regulatory protein SIR2 homolog 2 {ECO:0000255|HAMAP-Rule:MF_03161}; SIR2-related protein 2 | 3659310 |
| 446899 | SIR4_MOUSE | D3Z1D9; Q8R216 | Sirt4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03161, ECO:0000303|PubMed:25525879}; 2.3.1.- {ECO:0000255|HAMAP-Rule:MF_03161, ECO:0000305|PubMed:25525879}; NAD-dependent ADP-ribosyltransferase sirtuin-4 {ECO:0000255|HAMAP-Rule:MF_03161}; 2.4.2.- {ECO:0000255|HAMAP-Rule:MF_03161}; NAD-dependent protein biotinylase sirtuin-4 {ECO:0000255|HAMAP-Rule:MF_03161}; 2.3.1.- {ECO:0000255|HAMAP-Rule:MF_03161}; NAD-dependent protein deacetylase sirtuin-4 {ECO:0000255|HAMAP-Rule:MF_03161}; 2.3.1.286 {ECO:0000255|HAMAP-Rule:MF_03161}; Regulatory protein SIR2 homolog 4 {ECO:0000255|HAMAP-Rule:MF_03161}; SIR2-like protein 4 {ECO:0000255|HAMAP-Rule:MF_03161} | 75387 |
| 446898 | SIR4_MONBE | A9UVV1 | | NAD-dependent protein deacylase SIR4 {ECO:0000255|HAMAP-Rule:MF_03161}; 2.3.1.286 {ECO:0000255|HAMAP-Rule:MF_03161}; Regulatory protein SIR2 homolog 4 {ECO:0000255|HAMAP-Rule:MF_03161} | 5890058 |
| 446897 | SIR4_LEIMA | Q4QB33 | SIR2rp2 | NAD-dependent protein deacylase SIR2rp2 {ECO:0000255|HAMAP-Rule:MF_03161}; 2.3.1.286 {ECO:0000255|HAMAP-Rule:MF_03161}; Regulatory protein SIR2 homolog 2 {ECO:0000255|HAMAP-Rule:MF_03161}; SIR2-related protein 2 | 5652114 |
| 446896 | SIR4_HUMAN | O43346; Q32M33; Q9Y6E7 | SIRT4 {ECO:0000255|HAMAP-Rule:MF_03161, ECO:0000312|HGNC:HGNC:14932} | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03161, ECO:0000303|PubMed:25525879}; 2.3.1.- {ECO:0000255|HAMAP-Rule:MF_03161, ECO:0000269|PubMed:24052263, ECO:0000269|PubMed:25525879}; NAD-dependent ADP-ribosyltransferase sirtuin-4 {ECO:0000255|HAMAP-Rule:MF_03161}; 2.4.2.- {ECO:0000255|HAMAP-Rule:MF_03161}; NAD-dependent protein biotinylase sirtuin-4 {ECO:0000255|HAMAP-Rule:MF_03161}; 2.3.1.- {ECO:0000255|HAMAP-Rule:MF_03161, ECO:0000269|PubMed:25525879}; NAD-dependent protein deacetylase sirtuin-4 {ECO:0000255|HAMAP-Rule:MF_03161}; 2.3.1.286 {ECO:0000255|HAMAP-Rule:MF_03161}; Regulatory protein SIR2 homolog 4 {ECO:0000255|HAMAP-Rule:MF_03161}; SIR2-like protein 4 {ECO:0000255|HAMAP-Rule:MF_03161} | 23409 |
| 446895 | SIR4_DROME | D0IQB9; Q8IRR5; Q9W4A1 | Sirt4 | NAD-dependent protein deacylase Sirt4 {ECO:0000255|HAMAP-Rule:MF_03161}; 2.3.1.286 {ECO:0000255|HAMAP-Rule:MF_03161}; Regulatory protein SIR2 homolog 4 {ECO:0000255|HAMAP-Rule:MF_03161} | 31480 |
| 446894 | SIR4_BOVIN | Q1JQC6 | SIRT4 {ECO:0000255|HAMAP-Rule:MF_03161} | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03161}; 2.3.1.- {ECO:0000255|HAMAP-Rule:MF_03161}; NAD-dependent ADP-ribosyltransferase sirtuin-4 {ECO:0000255|HAMAP-Rule:MF_03161}; 2.4.2.- {ECO:0000255|HAMAP-Rule:MF_03161}; NAD-dependent protein biotinylase sirtuin-4 {ECO:0000255|HAMAP-Rule:MF_03161}; NAD-dependent protein deacetylase sirtuin-4 {ECO:0000255|HAMAP-Rule:MF_03161}; 2.3.1.286 {ECO:0000255|HAMAP-Rule:MF_03161}; Regulatory protein SIR2 homolog 4 {ECO:0000255|HAMAP-Rule:MF_03161}; SIR2-like protein 4 {ECO:0000255|HAMAP-Rule:MF_03161} | 519328 |
| 446893 | SIR4_BATDJ | F4P804 | | NAD-dependent protein deacylase SIR4 {ECO:0000255|HAMAP-Rule:MF_03161}; 2.3.1.286 {ECO:0000255|HAMAP-Rule:MF_03161}; Regulatory protein SIR2 homolog 4 {ECO:0000255|HAMAP-Rule:MF_03161} | 18237484 |
| 446892 | SIR4_ARATH | B9DFU7; F4KCI0; Q94AQ6; Q9FY91 | SRT2 {ECO:0000303|PubMed:20573705} | NAD-dependent protein deacylase SRT2 {ECO:0000255|HAMAP-Rule:MF_03161}; 2.3.1.286 {ECO:0000255|HAMAP-Rule:MF_03161}; Regulatory protein SIR2 homolog 2 {ECO:0000255|HAMAP-Rule:MF_03161} | 830782 |
| 446891 | SIR42_CAEEL | Q20481 | sir-2.3 | NAD-dependent protein deacylase sir-2.3 {ECO:0000255|HAMAP-Rule:MF_03161}; 2.3.1.286 {ECO:0000255|HAMAP-Rule:MF_03161}; Regulatory protein SIR2 homolog 3 {ECO:0000255|HAMAP-Rule:MF_03161} | 185876 |
| 446890 | SIR41_CAEEL | D1MN70; Q20480; Q7JMD3 | sir-2.2 | NAD-dependent protein deacylase sir-2.2 {ECO:0000255|HAMAP-Rule:MF_03161}; 2.3.1.286 {ECO:0000255|HAMAP-Rule:MF_03161}; Regulatory protein SIR2 homolog 2 {ECO:0000255|HAMAP-Rule:MF_03161} | 181455 |
| 446889 | SIR3_YEAST | D6VZ77; E9P924; P06701 | SIR3 | Regulatory protein SIR3; Silent information regulator 3 | 851163 |
| 446888 | SIR3_MOUSE | B9W0A9; C6ZII7; Q8R104; Q9EPA8 | Sirt3 | NAD-dependent protein deacetylase sirtuin-3; 2.3.1.286 {ECO:0000269|PubMed:21858060, ECO:0000269|PubMed:26620563, ECO:0000305|PubMed:17923681, ECO:0000305|PubMed:18794531, ECO:0000305|PubMed:21172655, ECO:0000305|PubMed:23835326}; Regulatory protein SIR2 homolog 3; SIR2-like protein 3; mSIR2L3 | 64384 |
| 446887 | SIR3_HUMAN | B7Z5U6; Q9NTG7; Q9Y6E8 | SIRT3 | NAD-dependent protein deacetylase sirtuin-3, mitochondrial; hSIRT3; 2.3.1.286 {ECO:0000269|PubMed:12186850, ECO:0000269|PubMed:12374852, ECO:0000269|PubMed:16788062, ECO:0000269|PubMed:18680753, ECO:0000269|PubMed:18794531, ECO:0000269|PubMed:19535340, ECO:0000269|PubMed:24121500}; Regulatory protein SIR2 homolog 3; SIR2-like protein 3 | 23410 |
| 446886 | SIR2_YEAST | D6VRV4; P06700 | SIR2 | NAD-dependent histone deacetylase SIR2; 2.3.1.286; Regulatory protein SIR2; Silent information regulator 2 | 851520 |
| 446885 | SIR2_TRYB2 | D6XK87; O96670; Q57V41 | SIR2rp1 | NAD-dependent protein deacetylase SIR2rp1; 2.3.1.286; Regulatory protein SIR2 homolog 1; SIR2-related protein 1 | 3658380 |
| 446884 | SIR2_SCHPO | O94640; Q6H8I3 | sir2 | NAD-dependent histone deacetylase sir2; 2.3.1.286; Regulatory protein sir2; Silent information regulator 2 | 3361342 |
| 446883 | SIR2_RAT | Q5RJQ4 | Sirt2 | NAD-dependent protein deacetylase sirtuin-2; 2.3.1.286 {ECO:0000305|PubMed:17344398}; NAD-dependent protein defatty-acylase sirtuin-2 {ECO:0000305}; 2.3.1.- {ECO:0000250|UniProtKB:Q8IXJ6}; Regulatory protein SIR2 homolog 2; SIR2-like protein 2 | 361532 |
| 446882 | SIR2_PONAB | Q5RBF1 | SIRT2 | NAD-dependent protein deacetylase sirtuin-2; 2.3.1.286 {ECO:0000250|UniProtKB:Q8IXJ6}; NAD-dependent protein defatty-acylase sirtuin-2 {ECO:0000305}; 2.3.1.- {ECO:0000250|UniProtKB:Q8IXJ6}; Regulatory protein SIR2 homolog 2; SIR2-like protein 2 | 100172430 |
| 446881 | SIR2_MYCPA | Q73XV0 | sir2 | Sulfite reductase [ferredoxin] 2; 1.8.7.1 | 0 |
| 446880 | SIR2_MOUSE | E9PXF5; Q8VDQ8; Q9CXS5; Q9EQ18; Q9ERJ9; U5TP50 | Sirt2 | NAD-dependent protein deacetylase sirtuin-2; 2.3.1.286 {ECO:0000269|PubMed:17521387, ECO:0000269|PubMed:17574768, ECO:0000269|PubMed:17681146, ECO:0000269|PubMed:21841822}; NAD-dependent protein defatty-acylase sirtuin-2 {ECO:0000305}; 2.3.1.- {ECO:0000250|UniProtKB:Q8IXJ6}; Regulatory protein SIR2 homolog 2; SIR2-like protein 2; mSIR2L2 | 64383 |
| 446879 | SIR2_MACFA | Q4R834 | SIRT2 | NAD-dependent protein deacetylase sirtuin-2; 2.3.1.286 {ECO:0000250|UniProtKB:Q8IXJ6}; NAD-dependent protein defatty-acylase sirtuin-2 {ECO:0000305}; 2.3.1.- {ECO:0000250|UniProtKB:Q8IXJ6}; Regulatory protein SIR2 homolog 2; SIR2-like protein 2 | 0 |
| 446878 | SIR2_LEIMA | Q25337; Q4Q9H0 | SIR2rp1 | NAD-dependent protein deacetylase SIR2rp1; 2.3.1.286; Regulatory protein SIR2 homolog 1; SIR2-related protein 1 | 5652751 |
| 446877 | SIR2_KLULA | P33294; Q6CK00 | SIR2 | NAD-dependent histone deacetylase SIR2; 2.3.1.286; Regulatory protein SIR2; Silent information regulator 2 | 2895003 |
| 446876 | SIR2_HUMAN | A8K3V1; B2RB45; O95889; Q8IXJ6; Q924Y7; Q9P0G8; Q9UNT0; Q9Y6E9; U5TP13 | SIRT2 | NAD-dependent protein deacetylase sirtuin-2; 2.3.1.286 {ECO:0000269|PubMed:11483616, ECO:0000269|PubMed:11812793, ECO:0000269|PubMed:16648462, ECO:0000269|PubMed:18722353, ECO:0000269|PubMed:24177535, ECO:0000269|PubMed:24940000, ECO:0000269|PubMed:25672491}; NAD-dependent protein defatty-acylase sirtuin-2 {ECO:0000305}; 2.3.1.- {ECO:0000269|PubMed:25704306, ECO:0000269|PubMed:29239724, ECO:0000269|PubMed:32103017}; Regulatory protein SIR2 homolog 2; SIR2-like protein 2 | 22933 |
| 446875 | SIR2_DANRE | Q7ZVK3 | sirt2 | NAD-dependent protein deacetylase sirtuin-2; 2.3.1.286 {ECO:0000305|PubMed:24940000}; NAD-dependent protein defatty-acylase sirtuin-2 {ECO:0000305}; 2.3.1.- {ECO:0000250|UniProtKB:Q8IXJ6}; Regulatory protein SIR2 homolog 2; SIR2-like protein 2 | 322309 |
| 446874 | SIR2_CANGA | Q6FWI7 | SIR2 | NAD-dependent histone deacetylase SIR2; 2.3.1.286; Regulatory protein SIR2; Silent information regulator 2 | 2886842 |
| 446873 | SIR2_CANAL | A0A1D8PGB6; O59923; Q5AD75; Q5ADK3 | SIR2 {ECO:0000303|PubMed:10228170} | NAD-dependent histone deacetylase SIR2 {ECO:0000305}; 2.3.1.286 {ECO:0000250|UniProtKB:P06700}; Regulatory protein SIR2 {ECO:0000305}; Silent information regulator 2 {ECO:0000305} | 3638845 |
| 446872 | SIR2_CAEEL | Q21921 | sir-2.1 {ECO:0000312|WormBase:R11A8.4a} | NAD-dependent protein deacetylase sir-2.1; 2.3.1.286; Protein sir-2.1; Regulatory protein SIR2 homolog 1 | 177924 |
| 446871 | SIR2_CAEBR | A8WJ80; Q60L58 | sir-2.1 | NAD-dependent protein deacetylase sir-2.1; 2.3.1.286; Protein sir-2.1; Regulatory protein SIR2 homolog 1 | 8589890 |
| 446870 | SIR2_ASHGO | Q757M7 | SIR2 | NAD-dependent histone deacetylase SIR2; 2.3.1.286; Regulatory protein SIR2; Silent information regulator 2 | 4621047 |
| 446869 | SIR2E_DICDI | Q55DB0 | sir2E | NAD-dependent deacetylase sir2E; 2.3.1.286; Silent information regulator 2E | 8617175 |
| 446868 | SIR2D_DICDI | Q54GV7 | sir2D | NAD-dependent deacetylase sir2D; 2.3.1.286; Silent information regulator sir2D | 8627377 |
| 446867 | SIR2C_DICDI | Q54P49 | sir2C | NAD-dependent deacetylase sir2C; 2.3.1.286; Silent information regulator sir2C | 8624779 |
| 446866 | SIR2B_PLAF7 | A0A144A2E0; Q8IKW2 | Sir2B {ECO:0000303|PubMed:19402747} | NAD-dependent protein deacetylase Sir2B; PfSir2B {ECO:0000303|PubMed:19402747}; 2.3.1.286 {ECO:0000255|PROSITE-ProRule:PRU00236}; Regulatory protein SIR2 homolog B; SIR2-like protein B | 812071 |
| 446865 | SIR2B_DICDI | Q54LF0 | sir2B | NAD-dependent deacetylase sir2B; 2.3.1.286; Silent information regulator sir2B | 8625751 |
| 446864 | SIR2A_PLAF7 | Q8IE47 | Sir2A {ECO:0000303|PubMed:19402747} | NAD-dependent protein deacylase Sir2A {ECO:0000255|HAMAP-Rule:MF_03160}; 2.3.1.- {ECO:0000255|HAMAP-Rule:MF_03160, ECO:0000269|PubMed:21992006}; PfSir2 {ECO:0000303|PubMed:15820676}; PfSir2A {ECO:0000303|PubMed:19402747}; Regulatory protein SIR2 homolog A | 814122 |
| 446863 | SIR2A_DICDI | Q54QE6 | sir2A | NAD-dependent deacetylase sir2A; 2.3.1.286; Silent information regulator sir2A | 8624322 |
| 446862 | SIR24_CAEEL | Q95Q89 | sir-2.4 | NAD-dependent protein deacetylase sir-2.4; 2.3.1.286; Regulatory protein SIR2 homolog 4; SIR2-like protein 4 | 182284 |
| 446861 | SIR1_YEAST | D6VXG2; P21691 | SIR1 | Regulatory protein SIR1; Heterochromatin protein SIR1; Silent information regulator 1 | 853976 |
| 446860 | SIR1_YEAS7 | A7A061 | SIR1 | Regulatory protein SIR1; Heterochromatin protein SIR1; Silent information regulator 1 | 0 |
| 446859 | SIR1_YEAS6 | B5VMP2 | SIR1 | Regulatory protein SIR1; Heterochromatin protein SIR1; Silent information regulator 1 | 0 |
| 446858 | SIR1_YEAS1 | B3LRH6 | SIR1 | Regulatory protein SIR1; Heterochromatin protein SIR1; Silent information regulator 1 | 0 |
| 446857 | SIR1_TOBAC | O82802 | SIR1 | Sulfite reductase 1 [ferredoxin], chloroplastic; NtSiR1; 1.8.7.1 | 107780886 |
| 446856 | SIR1_RAT | A0A0G2JZ79 | Sirt1 {ECO:0000312|RGD:1308542} | NAD-dependent protein deacetylase sirtuin-1 {ECO:0000250|UniProtKB:Q923E4}; 2.3.1.286 {ECO:0000250|UniProtKB:Q96EB6}; NAD-dependent protein deacylase sirtuin-1; 2.3.1.- {ECO:0000250|UniProtKB:Q923E4} | 0 |
| 446855 | SIR1_ORYSI | B8ARK7; Q9XGT1 | SRT1 | NAD-dependent protein deacetylase SRT1; 2.3.1.286; Regulatory protein SIR2 homolog 1; SIR2-like protein 1 | 0 |
| 446854 | SIR1_MYCPA | Q73YC1 | sir1 | Sulfite reductase [ferredoxin] 1; 1.8.7.1 | 0 |
| 446853 | SIR1_MOUSE | Q923E4; Q9QXG8 | Sirt1 | NAD-dependent protein deacetylase sirtuin-1; 2.3.1.286 {ECO:0000269|PubMed:20167603, ECO:0000269|PubMed:28883095}; NAD-dependent protein deacylase sirtuin-1 {ECO:0000305}; 2.3.1.- {ECO:0000305|PubMed:30026585}; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; SIR2alpha; Sir2; mSIR2a; 75SirT1 | 93759 |
